45. ______ is known to us is that the old doctor, for ______ life was hard in the past, still works very hard in his late life.

A. As; whom　　 B. What; whom　　 C. It; whose　　 D. As; whose

44. Helen, when you receive some e-mails, don’t answer any e-mail ____ your private information, however official they look.

A. seeking　　 B. asking　　　 C. requesting　　 D. accepting

43. The famous painting that is __________ so much praise can be seen in the museum.

A. with　　　 B. beyond　　　　 C. without　　 D. within

42. __________ you are familiar with the author’s ideas, try reading all the sections as quickly as possible.

A. Now　　　 B. Ever since　　　 C. So that　　 D. As long as

41. A short, thin man, __________ past middle age, visited the manager and applied for the job.

A. much　　　 B. well　　　 C. too　　　 D. highly

40. As we all know, ____ medical examination will help us find out health problems as early as possible.

A. normal　　 B. general　　　 C. common　　　 D. regular

39. The next day, the group of villagers had not gone very far ____ they entered a very narrow passage between two mountains.

A. after　　　 B. when　　　　 C. until　　　 D. while

38. Alone in a deserted house, he was so busy with his writing that he felt ________ lonely.

A. nothing but　　 B. anything but　　 C. all but　　 D. everything but

37. The editor-in-chief asked me to write another article for them, ________ about how to prevent bird flu.

A. that 　　　B. one　　　 C. it　　　 D. what

36. Though it’s a challenging job, he did it ________ it took me.

A. one-third a time B. one-third time C. the one-third time D. one-third the time