What’s the matter with you?

A．the wrong         B．trouble           C．wrong            D．the weather

——You have a fever. What’s the matter with you?
——H7N9 is coming now. I have to see the doctor.

What’s ____ with you, Ann?
A. the matter    B. the wrong   C. matter

 ----What’s up ?

----I failed in the examination of Physics.　

A. How are you?               B. What’s matter with you?

C. What are you doing?          D. What’s wrong with you?

——You have a fever. What’s the matter with you?

——H7N9 is coming now. I have to see the doctor.

A．wrong .           B．worry            C．illness            D．pain