题目内容

He tried his best to solve the problem,________ difficult it was.
A．howeverB．no matter
C．whateverD．although
A?
however+adj./adv.引导让步状语从句，意为“无论多么”。no matter不能单独使用，后须加what/how/when/where等连词。C、D两项后不能接形容词，故答案为A。
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