15.HIV is a tricky virus that escapes typical immune responses.During a successful immune system response to a foreign body,white blood cells produce antibodies that target the foreign body.These antibodies then mark the foreign body for destruction by other immune cells.For the most part,HIV escapes these immune defenses,but rare individuals develop antibodies that effectively block the virus.Researchers are now showing that these antibodies can also act as treatments in other HIV patients.
HIV has several ways of escaping the immune response.Unlike most viruses,HIV specifically attacks a type of white blood cell that is critical to our immune system.During reproduction,the HIV virus also picks up many new mutations (变异),which often change it enough that any antibodies produced earlier during the infection no longer recognize it.
These rare antibodies can also keep the virus from infecting new cells,which could make them an effective treatment.In animal studies,injection of low concentrations of these antibodies could act as a vaccine (疫苗) and provide protection against infection.Injections can even control active infections when combined with additional antibodies that target other molecules (分子) on the HIV surface.These findings led to humans phase 1clinical trials to evaluate a specific antibody that targets HIV.This study revealed that a single injection of the antibody typically reduced the presence of HIV in the blood of patients who have viruses that were sensitive to the antibody.
After performing test-tube studies showing the effectiveness of the antibody,the researchers evaluated its safety in humans in a small trial.The study included two groups of participants:14uninfected individuals and 19individuals with an HIV-1infection.The researchers then tracked the clearance of the antibody by following its levels in the participants'blood.Consistent with previous studies,HIV-1infected individuals exhibited faster clearance of the antibody,with a half-life of 12.8days compared to 24.0days for uninfected participants.Despite the fast clearance,however,the antibody appeared to be effective.
Thirteen HIV-1infected participants with the highest levels of virus received the highest dose (剂量) of the antibody.Eleven of them showed a rapid decline in HIV levels.Tracking the infection through the first weeks after treatment revealed the evolution of multiple viruses that were no longer affected by the antibody.However,these new variants (变体) generally remained sensitive to antibodies targeting other virus surface molecules.
Overall,this investigation shows the safety of injections of antibody 10-1074in humans.Thus,researchers may be able to build a cocktail of antibodies that effectively block active HIV infections.

59.HIV escapes immune responses byC.
A.removing the foreign body
B.identifying the immune system
C.attacking a certain white blood cell
D.reproducing some effective antibodies
60.What does the underlined word"it"in Paragraph 2refer to?C
A.The immune system.
B.A type of white blood cell.
C.The HIV virus.
D.An antibody.
61.The purpose of the further study of antibodies is toD.
A.introduce a vaccine protecting humans against infection
B.confirm the reduction of HIV in the blood of the patients
C.track a faster clearance of antibodies in uninfected subjects
D.prove the safety and effectiveness of antibodies in humans
62.What can we infer from the passage?B
A.Antibodies remain ineffective against most HIV viruses.
B.Researchers feel optimistic about a new cure for HIV.
C.Researchers get contradictory findings from a series of studies.
D.Antibodies can evolve with HIV viruses from infected patients.
12.A MAJOR breakthrough that could save many lives could be coming,as a simple blood test from genomics (基因组学) company Illumina could help to detect (发现)cancer early.
The company,helped by $100 million (about 658 million yuan)from famous tech founders like Bill Gates and Jeff Bezos,aims to find warning signs of any type of cancer before there are any symptoms or tumors (肿瘤),and thus save many lives,according to The Telegraph.
The race to invent this type of technology is happening between several scientists.For example,the Cancer Research UK Manchester Institute and the University of Leicester in the UK are both working on similar technologies.
Although some blood treatments that show tumors returning or cancer getting worse have been developed,scientists have been trying for some time to find cancer signs in people that otherwise seem healthy.The technology,called"liquid biopsy",would work by finding parts of DNA that are known to be signs of cancer in the blood as the disease developed.
Catching cancer early isn't always a good thing-some cancers never go on to become dangerous,but treating them can have bad side effects.However,Jay Flatley,the Illumina chief executive and chairman of Grail,a company set up by Illumina,told The New York Times that Grail will solve these issues by sequencing(确定…的顺序)the DNA of 30,000 to 50,000 people.It will check how serious their cancers are over time to make the test accurate.The money of a large company like Illumina means that its DNA sequencing technologies are far more accurate than the average ones.
At the University of Leicester,researchers such as Professor Jacqui Shaw are also trying to solve the problem by analyzing bits of DNA for errors that are only related to fast-progressing tumors.
"We hope today is a turning point in the war on cancer,"said Flatley."By making it possible for cancer to be detected early in people with no symptoms through a simple blood test,we aim to greatly decrease cancer deaths by finding the disease at a stage when it can be cured."
Last year,a similar test created in London by the Institute of Cancer Research was able to tell if breast cancer was coming back almost eight months before any symptoms were found.

59.According to the article,the company IlluminaD.
A.has invented a new medicine to cure cancer
B.has found a new way to cure cancer of any kind
C.is developing a new treatment for breast cancer
D.could use a blood test to catch cancer early
60.What can be concluded from the article?C
A.Blood tests still can't discover signs of cancer returning.
B.Only scientists in the UK are making progress in cancer research.
C.Finances play an important role in research.
D.The"liquid biopsy"technology is the first blood treatment adopted in the history of cancer research.
61.The author wrote the article mainly toA.
A.inform us of a new method of detecting cancer
B.call for donations to companies doing medical research
C.compare different cancer experiments
D.stress the difficulties of medical research.
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