Question

Madam Curie ________ the honors that were given to her in her later years．

1. A.
   took little notice of
2. B.
   took much notice of
3. C.
   had taken little notice of
4. D.
   had taken much notice of

Answer 1

A
“take no/little/much notice of…．．．”意为“不留心；很少留心；很留心”；根据in her later years可以判断应该用一般过去时。