Experts hope an experimental drug can be as effective against the novel coronavirus in people as it has been on cells in a controlled lab environment.

The US drug, remdesivir (瑞德西韦), began clinical trials(临床试验)on patients in Wuhan, Hubei province on Thursday. Other medications, including chloroquine, arbidol and darunavir have also recently been found capable of arresting viral growth in lab cells, but like remdesivir, they require more clinical trials to confirm their safety and potency on humans.

The Phase III trials for remdesivir have been approved by China’s National Medical Products Administration and is conducted by the China-Japan Friendship Hospital in Beijing and the Chinese Academy of Medical Sciences on patients at the Wuhan Jinyintan Hospital.

“A total of 761 patients will participate in two trials-one trial to assess the drugs' potency on 308 cases with mild or moderate infection, and the other on 453 severely infected patients”, Cao Bin, head of the clinical trial and vice-president of the friendship hospital, said on Wednesday.

Cao said studies have shown remdesivir is effective in inhibiting the growth of the novel coronavirus in vitro(在生物体外), meaning the procedure was done on cells in a controlled environment outside of a living organism, typically in a petri dish or test tube.

But the drug has yet to show convincing clinical evidence that it can translate its positive in vitro results into actual human patients. So, it will require strict clinical testing, Cao said.

A 35-year-old patient from the United States infected with the virus was reported seeing noticeable improvement with no obvious side effects after taking the drug, according to the New England Journal of Medicine.

Gilead Sciences, the maker of remdesivir, said in a recent statement that it has been working with government agencies on the novel coronavirus response efforts.

However, the company stressed that remdesivir is an experimental medicine that has only been used in a handful of patients, “so we do not have an appropriately full understanding of the effect of this drug ”.

1.Why does the US drug, remdesivir, began clinical trials?

A.To replace the traditional medicine.

B.To confirm their safety and potency on humans.

C.To show whether remdesivir is effective in inhibiting the growth of the novel coronavirus in vitro.

D.To see how it takes effect.

2.What is true according to the passage?

A.After taking the drug, a 35-year-old patient was infected with the virus.

B.Doctors had seen noticeable success treating a 35-year-old patient infected with the virus.

C.Remdesivir can cure those who are infected with the novel coronavirus.

D.Chinese Hospital does The Phase III trials independently.

3.What’s the author's attitude towards the clinical trial of remdesivir?

A.Negative. B.Critical. C.Positive. D.Gloomy.

4.Where is this text most likely from?

A.A diary. B.A guidebook. C.A novel. D.A magazine.

The Erie Canal was the first important national waterway built in the US. It crossed New York State(州)from Buffalo on Lake Eric to Albany on the Hudson River. It joined the Great Lakes with the Atlantic Ocean.

Over the canal industrial goods(工业产品)could flow into the west, and materials could pour into the east. The Erie Canal helped New York develop into the nation's larges city.

The building of the canal was paid for completely by the state of New York. It cost $7,143,789, but it soon gained its price many times over. Between 1825, when the canal was opened, and 1882, when toll charges(过运河费)were stopped, the state collected $121,461,891.

For a hundred years before the Erie Canal was built, people had been talking about a canal to join the Great Lakes and the Atlantic Ocean. The man who planned the Erie Canal and carried the plan through was De Witt Clinton. At that time some people laughingly called it "Clinton's Ditch(沟)". Clinton talked and wrote about the canal and drew up plans for it. He and Governor Morris went to Washington in 1812 to ask for help for the canal, but they were unsuccessful.

Clinton became governor of New York State in 1817, and shortly afterwards, on July 4,1817, broke ground for the canal in Rome of New York State. The first part of the canal was completed in 1820. As the canal grew, towns along its course developed fast. The length of the canal is 363 miles.

1.According to the map and Paragraph 1 we can know that ______ into the Atlantic Ocean.

A.the Great Lakes flow B.the Hudson River flows

C.Lake Erie flows D.the Eric Canal flows

2.We can see that the Erie Canal ______.

A.joined the Great Lakes together B.crossed New York State from north to south

C.played an important part in developing New York City D.was the first waterway built in the US

3.______ paid for the building of the Erie Canal.

A.The government of US B.Ships through the canal

C.People living along the canal D.The state of New York

4.Which of the following is TRUE according to the passage?

A.It's 363 miles from the Great Lakes to the Atlantic Ocean

B.Many other states helped New York build the canal

C.All parts of the canal were completed at the same time.

D.Clinton started building the canal after he became governor.

5.The Erie Canal ______.

A.was open for 57 years

B.is also called "Clinton's Ditch"

C.was first built on July 4th, 1817

D.cost so much that it was stopped in 1882

阅读下面两篇短文,根据短文内容选择正确答案。

Costume party(化妆舞会) invitation

Hi, everybody! The Spring Festival is coming! Are you expecting a special time to welcome it? Do you want to just relax or enjoy? A wonderful costume party will surprise you! Come and join us! The party will be in the school music hall on January 24th.

Just put on your happy face, prepare your most beautiful clothes, and dress up as the characters from your favorite movies or stories.

We can have fun dancing, singing and talking. And here are many enjoyable games for you—fun card games, hide and seek(捉迷藏), guessing games.

Besides a great cake, some special foods such as Seven pasta and Olaf ice-cream are waiting for you! Hot dogs, snacks and juice will also be prepared.

The exciting moment: The luckiest guest will get two tickets to the movie Jiang Ziya as the prize

Please reply to Sophia at 187-6663-7890, by Saturday, January 18th.

1.How long will the party last?

A.3 hours B.6 hours. C.9 hours

2.Which one is true?

A.The party will be on Friday, January 24th.

B.The luckiest guest will get two party tickets.

C.Students can only have fun card games at the party.

3.What should Cathy do if she wants to go to the party?

A.She should buy some snacks and juice.

B.She should prepare some delicious food.

C.She should dress up as her favorite character.

4.Anyone who wants to take part in the party should reply before ________.

A.January 1st B.January 18th C.January 24th

5.What is the invitation for?

A.A costume party B.A surprise party C.A music party

违法和不良信息举报电话:027-86699610 举报邮箱:58377363@163.com

精英家教网