We tried ______ to persuade him to stay home, but at last, he went to the construction site despite his bad illness.

We tried ______ to persuade him to stay home, but at last, he went to the construction site despite his bad illness.

1. A.
   in case
2. B.
   in vain
3. C.
   in fact
4. D.
   in addition

 We tried        to persuade him to stay home, but at last, he went to the construct site in spite of his illness.

 A. in vain        B. in return.       C. in fact           D. in time