____ new cure for this disease that medical experts have recently developed proves to be ______ most effective, although it can not completely kill all the viruses.

A. A; a　　　 B. The; / C. /; the D. A; the

As___as 80 people lost their lives in the fire,____five firefighters .

A. much ;including　　　　　　　　　　 B. many ;including

C. much to; include 　　　　　　　　　　 D. many ;to include

In the 16-19 age group，32 of women smoke ______ 28 of men.?

　 A. comparing to 　 B. comparing with

　 C. compared to 　 D. compare with

If I ___ the way to New York, I ___.

A. knew / would drive B. knew/ will drive C. knew/ would have drive

D. had known/ would drive

Shanghai, ________ the west coast of the Pacific Ocean, is well known for “the Oriental Pearl”.

locating　 B. locating at　　 C. located on　　　　 D. located at

There are no easy answers to questions brought to us by the rapidly changing world, ____ we can try to turn challenges into opportunities.

A. so　　　　　　 B. but　　　　　 C. for　　　　　　 D. then

—Catherine，I have cleaned the room for you.?

—Thanks.You　　　　 it.I could manage it myself.?

A.needn’t do　　　 B.needn’t have done?　　

C.mustn’t do　　 D.shouldn’t have done

A terrible air crash happened over die Atlantic Ocean, ____150 passengers．

　 A．having killed　　　 B．killing　　　 C．killed　　 D．to kill

Fully __________ in looking after three children at home, she no longer has time to enjoy various activities in the club.

A. attached      B. occupied      C. contributed      D. devoted

After driving for 20 miles，Jackson realized that he ________in the wrong direction．

A．was driving　　　 B．drove　　　　　　 C．had been driving　 D．had driven